Brock Purdy

49ers quarterback Brock Purdy speaks to reporters ahead of San Francisco’s Week 14 game against the Chicago Bears on Sunday at Levi’s Stadium.

Matt Maiocco lists five 49ers to keep an eye on in San Francisco’s must-win game against the Chicago Bears on Sunday at Levi’s Stadium.

Matt Maiocco and Jennifer Lee Chan discuss rookie Isaac Guerendo’s big opportunity to fill the San Francisco’s starting running back role for the 49ers in their week 14 matchup vs. the Bears Sunday at Levi’s Stadium.

ESPN analyst and former NFL player Chris Canty made a bold argument for how the San Francisco 49ers should handle Brock Purdy’s contract extension.

Matt Maiocco sifts through 49ers fan reactions — and overreactions- after San Francisco’s blowout loss to the Buffalo Bills.

In this episode of 49ers Overreactions, NBC Sports Bay Area’s Matt Maiocco examines whether San Francisco’s reliance on Christian McCaffrey led to his knee injury.

On “49ers Talk,” co-hosts Matt Maiocco and Jennifer Lee Chan debate if San Francisco currently is one of the NFL’s worst teams following consecutive blowout losses in Weeks 12 and 13.

The 49ers’ PFF grades reflect the lopsided score from San Francisco’s loss to the Buffalo Bills on Sunday.

49ers tight end George Kittle was just as perplexed as anyone about his lack of targets in San Francisco’s loss to the Buffalo Bills on Sunday.

The San Francisco 49ers’ losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending conference champion since the 1970 merger.

49ers quarterback Brock Purdy speaks to reporters after San Francisco’s 35-10 loss to the Buffalo Bills on Sunday night at Highmark Stadium.

49ers tight end George Kittle speaks to reporters after San Francisco’s 35-10 loss to the Buffalo Bills on Sunday night at Highmark Stadium.

NBC Sports Bay Area’s Matt Maiocco and Jennifer Lee Chan join the “49ers Postgame Live” crew to analyze San Francisco’s 35-10 loss to the Buffalo Bills on Sunday at Highmark Stadium.

A lot of things did not go right for the San Francisco 49ers in their 35-10 loss to the Buffalo Bills in Week 13.

49ers RB Christian McCaffrey was dealt another blow after exiting San Francisco’s Week 13 matchup against the Bills.

Brock Purdy revealed what he thought about while standing on the sideline at the of the San Francisco 49ers’ loss to the Green Bay Packers last Sunday.

Meteorologists are projecting 20 to 30 inches of snow to fall in Orchard Park, NY before kickoff between the San Francisco 49ers and Buffalo Bills on Sunday night.

San Francisco 49ers quarterback Brock Purdy want to be smart coming back from injury, but ultimately will rely on his competitive nature in his return against the Buffalo Bills on Sunday.

49ers quarterback Brock Purdy speaks with reporters ahead of San Francisco’s Week 13 matchup against the Buffalo Bills on Sunday night.

49ers coach Kyle Shanahan speaks with reporters ahead of San Francisco’s Week 13 matchup against the Buffalo Bills on Sunday night.