DeMeco Ryans

Former 49ers defensive coordinator-turned-Houston Texans head coach, DeMeco Ryans, told NBC Sports Bay Area’s Jennifer Lee Chan he anticipates Robert Saleh’s return to San Francisco contributing to the team’s rebound during the 2025 NFL season.

While Deebo Samuel will garner lots of trade interest, two former members of the San Francisco 49ers’ organization were hesitant to tie their respective teams to the star wideout.

“49ers Talk” co-hosts Matt Maiocco and Jennifer Lee Chan discuss how Deebo Samuel’s image among San Francisco’s fanbase has faded since his trade request.

On “49ers Talk,” hosts Matt Maiocco and Jennifer Lee Chan highlight San Francisco’s “exclusive rights” free agents and explain the decisions the team may face.

49ers star Fred Warner largely credits ex-San Francisco defensive coordinator DeMeco Ryans for the Houston Texans’ win over the Los Angeles Chargers.

“49ers Talk” co-hosts Matt Maiocco and Jennifer Lee Chan sit down to discuss San Francisco’s potential defensive coordinator candidates, with Robert Saleh leading the pack

Jed York revealed the pride he takes in the success the 49ers’ coaching and staff tree has had around the NFL, and why he’s grown an appreciation for developing personnel within the organization.

49ers CEO Jed York shares why he was one of just three “no” votes against the league’s kickoff proposal that NFL owners approved Tuesday at their annual meeting in Orlando, Fla.

New 49ers defensive tackle Maliek Collins describes his transition from Houston and shares his excitement towards working with Kris Kocurek.

DeMeco Ryans was upset watching the 49ers’ Super Bowl LVIII loss and Dre Greenlaw’s Achilles injury play out.

49ers GM John Lynch discusses Brock Purdy’s meteoric rise to prominence in an exclusive 1-on-1 interview with “49ers Talk” host Matt Maiocco at the NFL Scouting Combine in Indianapolis.