A year ago, the 49ers’ season came down to a dramatic Week 18 matchup against the Los Angeles Rams.
Facing a scenario in which a loss would have eliminated them from the postseason, the 49ers rallied from a 17-0 deficit to pull off an overtime victory to punch their ticket to the playoffs.
Of course, the Rams avenged that loss with a victory over the 49ers in the NFC Championship Game en route to a Super Bowl title.
Stay in the game with the latest updates on your beloved Bay Area and California sports teams! Sign up here for our All Access Daily newsletter.
The NFL released the regular-season schedule on Thursday, and one of the more striking elements is that the 49ers-Rams series will be completed before the calendar flips to November.
The 49ers face the Rams in Week 4 at Levi’s Stadium in an Oct. 3 matchup on "Monday Night Football." The return game is Week 8 on Sunday, Oct. 30, at SoFi Stadium in Inglewood.
Here is a look at the rest of the 49ers’ 2022 schedule:
PRESEASON
San Francisco 49ers
Find the latest San Francisco 49ers news, highlights, analysis and more with NBC Sports Bay Area and California.
Week 1: Green Bay at 49ers, TBA
Week 2: 49ers at Minnesota, TBA
Week 3: 49ers at Houston, Aug. 25, 5 p.m.
REGULAR SEASON
Week 1: Sunday, Sept. 11 -- 49ers at Chicago, 10 a.m.
Week 2: Sunday, Sept. 18 -- Seattle at 49ers, 1:05 p.m.
Week 3: Sunday, Sept. 25 --49ers at Denver, 5:20 p.m.
Week 4: Monday, Oct. 3 -- L.A. Rams at 49ers, 5:15 p.m.
Week 5: Sunday, Oct. 9 -- 49ers at Carolina, 1:05 p.m.
Week 6: Sunday, Oct. 16 -- 49ers at Atlanta, 10 a.m.
Week 7: Sunday, Oct. 23 -- Kansas City at 49ers, 1:25 p.m.
Week 8: Sunday, Oct. 30 -- 49ers at L.A. Rams, 1:25 p.m.
Week 9 -- Bye
Week 10: Sunday, Nov. 13 -- L.A. Chargers at 49ers, 5:20 p.m.
Week 11: Monday, Nov. 21 -- 49ers vs. Arizona (Mexico City), 5:15 p.m.
Week 12: Sunday, Nov. 27 -- New Orleans at 49ers, 1:25 p.m.
Week 13: Sunday, Dec. 4 -- Miami at 49ers, 1:05 p.m.
Week 14: Sunday, Dec. 11 -- Tampa Bay at 49ers, 1:25 p.m.
Week 15: Thursday, Dec. 15 -- 49ers at Seattle, 5:15 p.m.
Week 16: Saturday, Dec. 24 -- Washington at 49ers, 1:05 p.m.
Week 17: Sunday, Jan. 1 -- 49ers at Las Vegas, 1:05 p.m.
Week 18: Sunday/Sunday, Jan. 7-8 -- Arizona at 49ers, TBA