Arizona Cardinals quarterback Kyler Murray will try to play Sunday against the 49ers, but it isn't looking good for the dual-threat star.
NFL Media's Ian Rapoport reported Sunday morning that Murray faces "an uphill battle" and there "isn’t a ton of optimism." Murray did not practice this week as he recovers from an ankle injury. If he can't go, veteran QB Colt McCoy would start against San Francisco.
Stay in the game with the latest updates on your beloved Bay Area and California sports teams! Sign up here for our All Access Daily newsletter.
There also is a chance the Cardinals are without their top receiver, too.
DeAndre Hopkins, who has only missed two games in his entire career, is battling a hamstring injury and also didn't practice all week. He's considered a game-time decision.
RELATED: Bosa is 'happy' for Kyler, pleased with 2019 draft result
Both Hopkins and Murray played against the 49ers earlier this season in a 17-10 win for Arizona. Hopkins had six receptions for 87 yards and a touchdown. Murray completed 22 of his 31 attempts for 239 yards and one TD.
San Francisco 49ers
Find the latest San Francisco 49ers news, highlights, analysis and more with NBC Sports Bay Area and California.
The Cardinals lead the NFC West at 7-1 while the 49ers are looking to get back to .500. A win would improve their record to 4-4.