49ers Analysis October 3, 2021 4:39 pm Lance replaces injured Garoppolo as 49ers lose to Seahawks While the 49ers started off hot both offensively and defensively, between Jimmy Garoppolo injuring his calf and Russell Wilson rebounding, the 49ers failed to get the win at Levi Stadium. 49ers videos 1:02 Smith reacts to being called toughest opponent Staley, Williams faced 2:01 Aldon Smith reflects on NFL career, lessons learned 2:51 Former 49er Aldon Smith shares message to youth on mental health 0:58 49ers Talk: 49ers sign Terrell Owen's son Terique as undrafted free agent 1:25 49ers Talk: Is ‘writing on the wall' for Samuel's future in San Francisco?
