Yes, things could get worse.
All the 49ers have to do is look across the field on Sunday. The New York Jets already did not have a lot of talent or depth. Now, their top running back, Le’Veon Bell, and their best receiver, Jamison Crowder, are out with hamstring injuries.
The 49ers, meanwhile, are coming off a difficult opening-week loss to the Arizona Cardinals. Cornerback Richard Sherman is out with a calf strain, and tight end George Kittle did not practice this week due to a left knee sprain.
The 49ers open back-to-back games in East Rutherford, New Jersey, against the Jets in Week 2. Then, they face the New York Giants in Week 3.
These are two games the 49ers must win. And they may need four of these five players to step to the forefront on Sunday to get this trip off to a good start: