Rookie defensive tackle Javon Kinlaw was ruled out of action with a knee injury, and will not be available for the 49ers' Week 16 game Saturday against the Arizona Cardinals.
Kinlaw is one of three defensive linemen who were listed among the 49ers' seven inactive players. Defensive end Dion Jordan (knee) and Kevin Givens also will not be in uniform. The 49ers on Friday announced Givens would not play in the game. The club said the deactivation was not due to an injury.
The 49ers' other inactive players are wide receivers Deebo Samuel (hamstring) and newly signed Matt Cole, as well as defensive backs Richard Sherman (calf) and Jimmie Ward (concussion).
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Kinlaw, whom the 49ers selected with the No. 14 overall pick, has started 12 of the 14 games in which he has appeared as a rookie. He has 33 tackles, 1.5 sacks and an interception return for a touchdown.
Tight end George Kittle will be in uniform Saturday for the first time since the 49ers' Week 8 game against the Seattle Seahawks on Nov. 1. Kittle has recovered from a fractured cuboid bone in his foot.
The 49ers made a number of roster moves on Friday to activate players to be eligible to play against the Cardinals:
--Offensive lineman Colton McKivitz was activated from the Reserve/COVID-19 List;
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--Defensive lineman Darrion Daniels was promoted to the active roster from the team's practice squad;
--Defensive lineman Alex Barrett and tight end Daniel Helm were activated from the team's practice squad (COVID-19 replacement);
--Cornerback Tim Harris and wide receiver Jordan Matthews were activated from the team's practice squad (standard elevation;
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The 49ers on Friday placed quarterback Nick Mullens (elbow) running back Raheem Mostert (ankle) on injured reserve.
Also, quarterback Jimmy Garoppolo remains on injured reserve with an ankle sprain that has kept him sidelined since Nov. 1. Garoppolo returned to practice this week. The 49ers did not activate him off IR, and he is not expected to play in the season finale against the Seahawks, either.
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