The 49ers will be missing two key defensive players in their "Sunday Night Football" clash against the Los Angeles Chargers.
Defensive ends Arik Armstead and Samson Ebukam were designated inactive 90 minutes before kickoff at Levi's Stadium. Armstead was ruled out of the game on Friday's injury report, but Ebukam was listed as questionable with quadricep and Achilles injuries.
Other inactive 49ers for Week 10: running back Ty Davis-Price, defensive end Kemoko Turay, linebacker Curtis Robinson and offensive lineman Nick Zakelj.
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Receivers Deebo Samuel and Jauan Jennings, along with fullback Kyle Juszczyk and linebacker Dre Greenlaw, who all missed San Francisco's 31-14 victory over the Rams before the bye, will be suiting up for the primetime clash.
Armstead hasn't played since the 49ers' 24-9 victory over the Los Angeles Rams on Oct. 3. However, he told NBC Sports Bay Area's Jennifer Lee Chan on Monday that he expects to make his return to the gridiron soon.
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The Chargers' offense, meanwhile, will be operating without its top two receivers in Keenan Allen and Mike Williams.
Here is the full list of the Chargers' inactives: