ST. LOUIS -- The 49ers compensated for the losses of receiver Kyle Williams and running back Kendall Hunter with a little more Ted Ginn and Brandon Jacobs.Now, receiver Mario Manningham's status is uncertain after sustaining a shoulder injury that forced him out of action in the fourth quarter of the 49ers' 16-13 overtime loss to St. Louis Rams."We won't know right away in terms of how that will affect him next week," 49ers coach Jim Harbaugh said.Manningham has been nursing a right shoulder injury since originally being injured Oct. 14 against the New York Giants. He missed one game due to the injury.Williams (knee) and Hunter (Achilles) were placed on season-ending injured reserve last week. On Sunday, the 49ers suited up rookie A.J. Jenkins for the second time this season. But Jenkins and backup quarterback Alex Smith were the only 49ers players who did not see action. Jenkins was the 49ers' No. 5 receiver in Sunday's game.Prior to Manningham's injury, the 49ers used Manningham, Ginn and Michael Crabtree in three-receiver formations against the Rams. Crabtree had strong game with seven receptions for 101 yards. Randy Moss saw action mostly in one-receiver sets.
Ginn had one reception for 1 yard. Colin Kaepernick's option pitch sailed over Ginn's head late in the fourth quarter. The miscue led to Janoris Jenkins' 2-yard fumble return.Frank Gore found it difficult to get anywhere against the Rams' defense, as he gained just 58 yards and a touchdown on 23 carries. Gore appeared to be favoring his left arm after a carry in overtime. Afterward, Gore said he was all right.Jacobs took over Hunter's role as the backup and managed just 6 yards on four rushing attempts. Rookie running back LaMichael James was not one of the 49ers' 46 active players.
Stay in the game with the latest updates on your beloved Bay Area and California sports teams! Sign up here for our All Access Daily newsletter.