Frank Gore defies Father Time. The same can't be said for running back LeSean McCoy.
McCoy, 31, was released by the Bills on Saturday morning as teams cut their rosters down to 53 players.
The six-time Pro Bowl running back ran for a career-low 514 yards last season in 14 games. He also didn't record a receiving touchdown for the first time since 2014.
Though the Bills have moved on from McCoy, he's sure to garner interest from many other teams around the league. Could one of those clubs be the 49ers?
San Francisco is set with their top two backs in Tevin Coleman and Matt Breida, but Jerick McKinnon might not play a snap for a second straight season due to issues with his knee. It's more likely, however, that general manager John Lynch has to make a decision on running back Jeff Wilson instead of adding McCoy.
Wilson carried the ball 20 times for 100 yards in the 49ers' preseason finale and had a solid showing throughout traning camp.
San Francisco 49ers
[RELATED: How reported Clowney trade to Seahawks could hurt 49ers]
One ball-carrier we know won't be a 49er this season is Gore. The 36-year-old last donned red and gold in 2014 and hasn't slowed down since. Gore ran for 722 yards last season in Miami and should get a fair share of carries in Buffalo with McCoy's departure.
Until he calls it quits, never count out Frank Gore.