PROGRAMMING NOTE: Giants-Cubs coverage begins at 4pm with Pregame Live on NBC Sports Bay Area and streaming right here.
After missing the last two games with a sprained left thumb, Denard Span is back at the top of the Giants lineup Wednesday in Chicago.
San Francisco Giants:
1. Denard Span (L) CF
2. Joe Panik (L) 2B
3. Brandon Belt (L) 1B
4. Buster Posey (R) C
5. Brandon Crawford (L) SS
6. Eduardo Nunez (R) LF
7. Christian Arroyo (R) 3B
8. Mac Williamson (R) RF
9. Matt Moore (L) P
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Chicago Cubs:
1. Javier Baez (R) 2B
2. Albert Almora Jr. (R) CF
3. Kris Bryant (R) 3B
4. Anthony Rizzo (L) 1B
5. Ian Happ (S) LF
6. Jason Heyward (L) RF
7. Addison Russell (R) SS
8. Miguel Montero (L) C
9. Kyle Hendricks (R) P